Boss Majhi Ladachi is a love story of Boss and her employee. The boss - Rajeshwari is weird by her nature due to her painful past with her family. She hates family and relationships. The only family members she has are her aunt and her cat Thakuli. Mihir, an architect by profession is working in her company. Mihir belongs to a big family. He has an allergy to cats. Mihir has lied this to retain his job and Rajeshwari is in dark about this. They both must get married to each other due to some unavoidable reasons. Will Rajeshwari come to know about his family? How will she react to it? How these two poll apart personalities will fall for each other? Will they be able to stay together?