Shaun and Lea head to the delivery room and everyone from the hospital is there, except for one very important person. A tragic accident involving Drs Perez and Kalu pulls everyone away, including Dr Murphy.
Dr Glassman and Dr Murphy's relationship may be irreparably damaged following a tense moment during surgery. Meanwhile, Dr Reznick struggles during her parental leave.
Dr. Marcus Andrews introduces some of the team to a patient whose optimism and faith seems to cause Dr. Asher Wolke the most skepticism in light of his own relationship with religion.
Drs. Andrews and Lim clash over a patient split nearly in half, which also reveals her issues with Dr. Kalu's return; Dr. Glassman gives Dr. Murphy some fatherly advice as they await news about Glassman's recent tests.
When a patient comes in with persistent and lingering COVID symptoms, the team discovers she may be dealing with something harder to treat; Andrews and Villanueva must contend with their hierarchy at the hospital and its effect on their relationship.
Dr. Shaun Murphy must learn how to work with Dr. Jared Kalu again and remind him that he must start all over at St. Bonaventure; Dr. Murphy treats a teenager suffering from neurological problems with a very high-risk procedure.
Dr. Shaun Murphy seeks legal representation to help him win a case and puts his faith in a promising, young lawyer who has obsessive compulsive disorder.
Dr. Jared Kalu makes a surprise return to San Jose's St. Bonaventure Hospital with his billionaire patient. Park must treat the man his wife had an affair with and try to find a way to forgive him.
When a 3-year-old arrives at the emergency room, the team immediately recognizes he is having a stroke; Dr. Shaun Murphy's diagnosis of the underlying cause doesn't solve the problem, which has Dr. Park searching deeper.
Shaun and Lea clash over their parenting styles and worry about what will happen to their relationship when their child is born; Dr. Lim must find a way to save the damaged lungs that one of her long-time patients has been waiting for.